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Most patients experience restored fertility after a transplant. For example, there is an advantage to transplantation over dialysis for kidney patients who want to have children.

For patients with cystic fibrosis, fertility problems may extend beyond transplant. In men, the vas deferns, the tube that normally carries the sperm from the testicles to the penis, may be blocked or defective. In women, fertility problems result from thick mucus blocking the cervix.

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